Beijing: We know that air pollution severely affects the respiratory system and the lungs, and it is also known to open the door to lung cancer, but all of this has now been closely monitored. Will also help.
Scientists have figured out a way for contaminated particles to affect the lungs, which could help us understand their cancer.
According to a report published in eLife, air pollution contains fine particulate matter (FPM) inhaled and has been identified as the number one threat to global health and cancer. But the details of the process were still hidden from view.
Zhen Zhen Wang, a professor at Nanjing University in China, says that FPMs do not directly cause cancer but play a direct role. One idea is that FPMs block the passage of security cells and they do not reach the place where they are needed properly.
To do this, scientists collected floating FPMs from air pollution in seven different regions of China and noted their effects on the most important immune cells that inhibit the growth of (cancerous) tumors. These immune cells are called cytotoxic T cells (CTL).
In the next phase, they were tested on mice that were not infected with any FPM. Mice that now contained FPM inhibited CTL activity, allowing cancer to flourish. It was found that the rats infected with the contaminated FPM particles had very slow penetration of CTL, which led to the growth of lung cancer.
The experts then studied the structure of the CTL and the tissues in depth. It turned out that the FPM did not allow the security cells to reach the right place. FPM dramatically transmits to lung tissue, and helper cells do not get there. It is now known that wherever FPM reaches, it alters the structure of cells and tissues.
By understanding this condition, experts will not only be able to understand lung cancer from pollution, but also pave the way for its treatment.