Cambridge: Scientists, looking at the DNA of cancer cells for the first time, have revealed what kind of cancerous components they have been exposed to, which experts have termed as cancer footprints.
In this regard, thousands of cancer cells have been studied which on the one hand will help us to know the cause of this cancer and on the other hand will help to treat every patient according to his condition.
Serena Nick Zenell, a genomics pharmacologist at Cambridge University, and her colleagues say we call it a sign of genetic mutations. These appear in the DNA of cancerous abscesses. This can be used to determine if the cause of the cancer in the patient is smoking, a chemical component, ultraviolet rays or an environmental cause.
This will allow doctors to understand each patient's tumor and determine the most useful and targeted treatment accordingly. But it should be noted that for this, the complete genome of many types of cancerous tumors has been studied and the changes that have taken place in it have been observed very closely.
Dr. Serena explains that there are many footprints on a beach sand that are difficult to understand. But a closer look reveals where these steps are going and where they are ending. In the same way, this research helps to find out who has the traces of the disease, that is, the genetic mutations, and where they are going.
For this, experts looked at the complete genome of more than 12,000 cancer cells and created a database.
Experts noted a total of 58 symptoms or genetic mutations that were additional causes of cancer and have yet to be understood. Experts have described them as a sign of a crime scene that leads us to the real thing. Interestingly, some of the changes are telling us which medicine will be effective and which treatment will be better. In this way it will be possible for each person to be treated for his or her specific cancer.
These changes have now been incorporated into the British Department of Health's database as part of the Fit MS tool. It is hoped that this will help in understanding the whole disease.
